Covid-19
As we have rapidly become aware, Covid-19 has provided a new twist now that the Omicron variant has emerged. Here are some insights from three Science Magazine articles not widely reported in mainstream media.
December 3, 2021 - New variant is better at evading immunity from past infections
The Omicron variant of Covid-19 has dozens of mutations which scientist worry might help it evade immunity. An analysis of 35,670 reinfections among 2.8 million positive tests in South Africa suggests that while “an earlier infection might help the new variant evade immunity … it looks like an earlier infection only offers half as much protection against Omicron as it does against Delta.” There are still a number of issues with the data, but “it is a good enough comparison to show us that … reinfections are a big deal with Omicron.”
December 1, 2021 - Where did ‘weird’ Omicron come from?
Scientists are puzzled as to how and where the Omicron variant emerged since it has so many mutations. “Omicron clearly did not develop out of one of the earlier variants of concern, such as Alpha or Delta. Instead, it appears to have evolved in parallel—and in the dark.” That raises the question of where Omicron’s predecessors lurked for more than a year. Scientists see essentially three possible explanations:
- The virus could have circulated and evolved in a population with little surveillance and sequencing.
- It could have gestated in a chronically infected COVID-19 patient.
- It might have evolved in a nonhuman species, from which it recently spilled back into people.
The theory that it “evolved and circulated in a hidden population” is the one that scientists think is most likely, but “It’s too early to rule out any theory about Omicron’s origin.”
November 27, 2021 - We won’t know for weeks how dangerous Omicron is
Scientists warn that it is too early to know whether Omicron is more infectious, more deadly, or better at reinfecting recovered people or evading vaccine-induced immunity. “One reason for concern about Omicron is that sequenced samples indicate it has rapidly replaced other variants in South Africa.” Scientists suspect it has spread to “many more places where it will be detected,” and epidemiologists are watching to learn how many people will be hospitalized and die. “All that will take time.”